| PLASMIC Score | Risk group | |
| 0 to 4 | Low | |
| 5 | Intermediate | |
| 6 to 7 | High | |
|
• Low risk (PLASMIC Scores ≤4): consider alternative diagnoses.
• Intermediate risk (PLASMIC Score 5): send ADAMTS-13 testing, keep close observation, obtain expert consultation, consider plasma exchange if no other cause identified. • High risk (PLASMIC Scores ≥6): send for ADAMTS-13 testing, obtain expert consultation, immediate plasma exchange *Severe deficiency was defined as ADAMTS13 activity level <15%. |
||
| 0 points | 1 points | |||
| Platelet count <30 x 109/L |
|
No
|
|
Yes
|
| Hemolysis* |
|
No
|
|
Yes
|
| Active cancer** |
|
Yes
|
|
No
|
| History of solid-organ or stem-cell transplant |
|
Yes
|
|
No
|
| MCV <9.0 x 10−14 L (<90 fL) |
|
No
|
|
Yes
|
| INR <1.5 |
|
No
|
|
Yes
|
| Creatinine <2.0 mg/dL (176.8 μmol/L) |
|
No
|
|
Yes
|
| Total score | Category |
| 0 | Low risk |
| Reset |